Research articles

Clijsters, L., Hoencamp, C., Calis, J.J.A., Marzio, A., Handgraaf, S.M., Cuitino, M.C., Rosenberg, B.R., Leone, G., Pagano, M. (2019) Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three E2F activators. Molecular Cell, 74, 1264-1277 pubmed

Cuitino, MC., Pecot, T., Sun, D., Kladney, R., Okano-Uchida, T., Shinde, N., Saeed, R., Perez-Castro, AJ., Webb, A., Liu, T., Bae, SI., Clijsters, L., Selner, N., Coppola, V., Timmers, C., Ostrowski, MC., Pagano, M., Leone, G. (2019) Two distinct E2F transcriptional modules drive cell cycles and differentiation. Cell Reports, 27, 3547-3560 pubmed

Dankert, J., Rona, G., Clijsters, L., Geter, P., Skaar, JR., Bermudez-Hernandez, K., Sassani, E., Fenyo, D., Ueberheide, B., Schneider, R., Pagano, M. (2016) Cyclin-F-mediated degradation of SLBP limits H2A.X accumulation and apoptosis upon genotoxic stress in G2. Molecular Cell, 64, 507-519 pubmed


Clijsters, L., van Zon, W., Riet, B.T., Voets, E., Boekhout, M., Ogink, J., Rumpf-Kienzl, C., Wolthuis, R. (2014) Inefficient degradation of cyclin B1 re-activates the spindle checkpoint right after sister chromatid disjunction. Cell Cycle, 13, 2370-2378 pubmed


Clijsters, L. and Wolthuis, R. (2014) PIP-box mediated degradation prohibits re-accumulation of Cdc6 during S-phase. Journal of Cell Science, 127, 1336-1345 pubmed


Clijsters, L., Ogink, J., Wolthuis, R. (2013). The spindle checkpoint, APC/C-Cdc20, and APC/C-Cdh1 play distinct roles in connecting mitosis to S phase. Journal of Cell Biology, 201, 1013-1026 pubmed


van Leuken, R., Clijsters, L., van Zon, W., Lim, D., Yao, X., Wolthuis, R. M., Yaffe, M. B., Medema, R. H., van Vugt, M. A. (2009). Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1. PLoS One, 4, e5282 pubmed


de Pater, E., Clijsters, L., Marques, S. R., Lin, Y. F., Garavito-Aguilar, Z. V., Yelon, D., Bakkers, J. (2009). Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development, 136, 1633-1641 pubmed


Nagel, R., Clijsters, L., Agami, R. (2009). The miRNA-192/194 cluster regulates the Period gene family and the circadian clock. FEBS Journal, 276, 5447-5455 pubmed

Review articles

van Leuken, R., Clijsters, L., Wolthuis, R. (2008). To cell cycle, swing the APC/C. Biochem Biophys Acta, 1786, 49-59 pubmed